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>   home   >   Products   >   Primary Antibodies   >   Neuroscience   >   NOS3 / eNOS Antibody (aa1186-1203)   

NOS3 / eNOS Antibody (aa1186-1203)

Rabbit Polyclonal Antibody

     
  • IHC - NOS3 / eNOS Antibody (aa1186-1203) ALS12133
    Anti-ENOS antibody IHC of human placenta.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IP
Primary Accession P29474
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 133kDa
Dilution IHC-P (1:50)
Additional Information
Gene ID 4846
Other Names Nitric oxide synthase, endothelial, 1.14.13.39, Constitutive NOS, cNOS, EC-NOS, Endothelial NOS, eNOS, NOS type III, NOSIII, NOS3
Target/Specificity Human eNOS amino acids 1186-1203 (RGAVPWAFDPPGSDTNSP)1,2,3
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
PrecautionsNOS3 / eNOS Antibody (aa1186-1203) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NOS3
Function Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets.
Cellular Location Cell membrane. Membrane, caveola. Cytoplasm, cytoskeleton. Golgi apparatus. Note=Specifically associates with actin cytoskeleton in the G2 phase of the cell cycle; which is favored by interaction with NOSIP and results in a reduced enzymatic activity
Tissue Location Platelets, placenta, liver and kidney.
Volume 125 µl
Research Areas
Citations (0)

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Background

Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets.

References

Janssens S.P.,et al.J. Biol. Chem. 267:14519-14522(1992).
Janssens S.P.,et al.J. Biol. Chem. 267:22694-22694(1992).
Marsden P.A.,et al.FEBS Lett. 307:287-293(1992).
Marsden P.A.,et al.J. Biol. Chem. 268:17478-17488(1993).
Nadaud S.A.,et al.Biochem. Biophys. Res. Commun. 198:1027-1033(1994).

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Discontinued
Cat# ALS12133
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