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BCAP31 / BAP31 Antibody (clone CC-1)

Rat Monoclonal Antibody

     
  • IHC - BCAP31 / BAP31 Antibody (clone CC-1) ALS12142
    Anti-BCAP31 / BAP31 antibody IHC of human spleen.
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, ICC, E, IP, IHC-Fr
Primary Accession P51572
Host Rat
Clonality Monoclonal
Clone Names CC-1
Calculated MW 28kDa
Dilution ICC (1:1000-1:10000), IHC-Fr (1:1000-1:10000), IHC-P (2.5 µg/ml), WB (1:1000-1:6000) ,
Additional Information
Gene ID 10134
Other Names B-cell receptor-associated protein 31, BCR-associated protein 31, Bap31, 6C6-AG tumor-associated antigen, Protein CDM, p28, BCAP31, BAP31, DXS1357E
Target/Specificity Recognizes an epitope (aa 230-246) encompassing a caspase recognition site and the ER-homing motif (KKEE), present at the C-terminus of human, primate, bovine and hamster BAP31. Does not recognize mouse and rat BAP31.
Reconstitution & Storage +4°C or -20°C, Avoid repeated freezing and thawing.
PrecautionsBCAP31 / BAP31 Antibody (clone CC-1) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name BCAP31
Synonyms BAP31, DXS1357E
Function Functions as a chaperone protein. Is one of the most abundant endoplasmic reticulum (ER) proteins. Plays a role in the export of secreted proteins in the ER, the recognition of abnormally folded protein and their targeting to the ER associated-degradation (ERAD). Also serves as a cargo receptor for the export of transmembrane proteins. May be involved in CASP8- mediated apoptosis.
Cellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. Note=May shuttle between the ER and the intermediate compartment/cis-Golgi complex
Tissue Location Ubiquitous. Highly expressed in neurons and discrete endocrine cells.
Research Areas
Citations (0)

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Background

Functions as a chaperone protein. Is one of the most abundant endoplasmic reticulum (ER) proteins. Plays a role in the export of secreted proteins in the ER, the recognition of abnormally folded protein and their targeting to the ER associated-degradation (ERAD). Also serves as a cargo receptor for the export of transmembrane proteins. May be involved in CASP8- mediated apoptosis.

References

Mosser J.,et al.Genomics 22:469-471(1994).
Li E.,et al.Eur. J. Biochem. 238:631-638(1996).
Adachi T.,et al.EMBO J. 15:1534-1541(1996).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Ross M.T.,et al.Nature 434:325-337(2005).

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$ 395.00
Cat# ALS12142
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