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CA2 / Carbonic Anhydrase II Antibody (HRP)

Rabbit Polyclonal Antibody

     
  • IHC - CA2 / Carbonic Anhydrase II Antibody (HRP) ALS12147
    Anti-Carbonic Anhydrase II antibody IHC of human kidney.
  • SPECIFICATION
  • CITATIONS
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  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P00918
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 29kDa
Dilution ELISA (1:1000-1:6000), IHC-P (5 µg/ml),
Additional Information
Gene ID 760
Other Names Carbonic anhydrase 2, 4.2.1.1, Carbonate dehydratase II, Carbonic anhydrase C, CAC, Carbonic anhydrase II, CA-II, CA2
Target/Specificity Assay by immunoelectrophoresis resulted in a single precipitin arc against anti peroxidase, anti rabbit serum, as well as purified and partially purified carbonic anhydrase II (human erythrocytes).
Reconstitution & Storage Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
PrecautionsCA2 / Carbonic Anhydrase II Antibody (HRP) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CA2
Function Essential for bone resorption and osteoclast differentiation (By similarity). Reversible hydration of carbon dioxide. Can hydrate cyanamide to urea. Involved in the regulation of fluid secretion into the anterior chamber of the eye. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption. Stimulates the chloride-bicarbonate exchange activity of SLC26A6.
Cellular Location Cytoplasm. Cell membrane. Note=Colocalized with SLC26A6 at the surface of the cell membrane in order to form a bicarbonate transport metabolon. Displaced from the cytosolic surface of the cell membrane by PKC in phorbol myristate acetate (PMA)-induced cells
Research Areas
Citations (0)

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Background

Essential for bone resorption and osteoclast differentiation (By similarity). Reversible hydration of carbon dioxide. Can hydrate cyanamide to urea. Involved in the regulation of fluid secretion into the anterior chamber of the eye. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption. Stimulates the chloride-bicarbonate exchange activity of SLC26A6.

References

Montgomery J.C.,et al.Nucleic Acids Res. 15:4687-4687(1987).
Murakami H.,et al.Genomics 1:159-166(1987).
Halleck A.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.

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$ 395.00
Cat# ALS12147
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