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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   CD105 Antibody (aa26-176)   

CD105 Antibody (aa26-176)

Rabbit Polyclonal Antibody

     
  • IHC - CD105 Antibody (aa26-176) ALS12156
    Anti-ENG / CD105 antibody IHC of human liver.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P
Primary Accession P17813
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 71kDa
Dilution IHC-P (1:100)
Additional Information
Gene ID 2022
Other Names Endoglin, CD105, ENG, END
Target/Specificity Recognizes human CD105.
Reconstitution & Storage Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
PrecautionsCD105 Antibody (aa26-176) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ENG
Synonyms END
Function Major glycoprotein of vascular endothelium. Involved in the regulation of angiogenesis. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors. Acts as TGF-beta coreceptor and is involved in the TGF- beta/BMP signaling cascade. Required for GDF2/BMP9 signaling through SMAD1 in endothelial cells and modulates TGF-beta1 signaling through SMAD3.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Endoglin is restricted to endothelial cells in all tissues except bone marrow
Volume 50 µl
Research Areas
Citations (0)

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Background

Major glycoprotein of vascular endothelium. Involved in the regulation of angiogenesis. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors. Acts as TGF-beta coreceptor and is involved in the TGF- beta/BMP signaling cascade. Required for GDF2/BMP9 signaling through SMAD1 in endothelial cells and modulates TGF-beta1 signaling through SMAD3.

References

Bellon T.,et al.Eur. J. Immunol. 23:2340-2345(1993).
Humphray S.J.,et al.Nature 429:369-374(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Gougos A.,et al.J. Biol. Chem. 265:8361-8364(1990).
McAllister K.A.,et al.Nat. Genet. 8:345-351(1994).

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$ 395.00
Cat# ALS12156
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