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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   MSN / Moesin Antibody   

MSN / Moesin Antibody

Mouse Monoclonal Antibody

     
  • IHC - MSN / Moesin Antibody ALS12160
    Anti-MSN / Moesin antibody IHC of human thymus.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, E, IP
Primary Accession P26038
Reactivity Human, Rat, Bovine
Host Mouse
Clonality Monoclonal
Calculated MW 68kDa
Dilution IHC-P (5 µg/ml), WB (1-2 µg/ml),
Additional Information
Gene ID 4478
Other Names Moesin, Membrane-organizing extension spike protein, MSN
Target/Specificity Recognizes 78kD moesin. Weakly recognizes 80kD radixin. Detects most of the proteolytic fragments of moesin. Does not react with talin or ezrin.
Reconstitution & Storage Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
PrecautionsMSN / Moesin Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MSN
Function Probably involved in connections of major cytoskeletal structures to the plasma membrane. May inhibit herpes simplex virus 1 infection at an early stage.
Cellular Location Cell membrane; Peripheral membrane protein; Cytoplasmic side Cytoplasm, cytoskeleton. Apical cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, microvillus membrane; Peripheral membrane protein; Cytoplasmic side. Note=Phosphorylated form is enriched in microvilli-like structures at apical membrane (By similarity). Increased cell membrane localization of both phosphorylated and non-phosphorylated forms seen after thrombin treatment. {ECO:0000250, ECO:0000269|PubMed:18586956}
Tissue Location In all tissues and cultured cells studied.
Volume 50 µl
Research Areas
Citations (0)

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Background

Probably involved in connections of major cytoskeletal structures to the plasma membrane. May inhibit herpes simplex virus 1 infection at an early stage.

References

Lankes W.T.,et al.Proc. Natl. Acad. Sci. U.S.A. 88:8297-8301(1991).
Ross M.T.,et al.Nature 434:325-337(2005).
Gevaert K.,et al.Nat. Biotechnol. 21:566-569(2003).
Reczek D.,et al.J. Cell Biol. 139:169-179(1997).
Urzainqui A.,et al.Immunity 17:401-412(2002).

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Discontinued
Cat# ALS12160
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