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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   XDH / Xanthine Oxidase Antibody   

XDH / Xanthine Oxidase Antibody

Rabbit Polyclonal Antibody

     
  • IHC - XDH / Xanthine Oxidase Antibody ALS12171
    Anti-Xanthine Oxidase antibody IHC staining of human liver.
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E, IP
Primary Accession P47989
Reactivity Human, Bovine
Host Rabbit
Clonality Polyclonal
Calculated MW 146kDa
Dilution ELISA (1:100000-1:400000), IHC-P (2.5 µg/ml),
Additional Information
Gene ID 7498
Other Names Xanthine dehydrogenase/oxidase, Xanthine dehydrogenase, XD, 1.17.1.4, Xanthine oxidase, XO, 1.17.3.2, Xanthine oxidoreductase, XOR, XDH, XDHA
Target/Specificity Recognizes bovine Xanthine Oxidase. Assay by IEP resulted in a single precipitin arc against anti-rabbit serum as well as purified and partially purified bovine buttermilk Xanthine Oxidase. Recognizes human Xanthine Oxidase in IHC-FFPE.
Reconstitution & Storage Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
PrecautionsXDH / Xanthine Oxidase Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name XDH
Synonyms XDHA
Function Key enzyme in purine degradation. Catalyzes the oxidation of hypoxanthine to xanthine. Catalyzes the oxidation of xanthine to uric acid. Contributes to the generation of reactive oxygen species. Has also low oxidase activity towards aldehydes (in vitro).
Cellular Location Cytoplasm. Peroxisome. Secreted
Tissue Location Detected in milk (at protein level). {ECO:0000269|Ref.12}
Research Areas
Citations (0)

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Background

Key enzyme in purine degradation. Catalyzes the oxidation of hypoxanthine to xanthine. Catalyzes the oxidation of xanthine to uric acid. Contributes to the generation of reactive oxygen species. Has also low oxidase activity towards aldehydes (in vitro).

References

Ichida K.,et al.Gene 133:279-284(1993).
Ichida K.,et al.Submitted (SEP-2000) to the EMBL/GenBank/DDBJ databases.
Xu P.,et al.Biochem. Biophys. Res. Commun. 199:998-1004(1994).
Xu P.,et al.Biochem. Biophys. Res. Commun. 215:429-429(1995).
Saksela M.,et al.Biochem. J. 315:235-239(1996).

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$ 395.00
Cat# ALS12171
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