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PTHR / PTHR1 Antibody

Mouse Monoclonal Antibody

     
  • IHC - PTHR / PTHR1 Antibody ALS12187
    Anti-PTH1R antibody IHC of human liver.
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  • SPECIFICATION
  • CITATIONS
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  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P
Primary Accession Q03431
Reactivity Human, Mouse, Monkey, Pig, Horse, Bovine, Dog
Host Mouse
Clonality Monoclonal
Calculated MW 66kDa
Dilution IHC-P (5 µg/ml), WB (0.5-2 µg/ml),
Additional Information
Gene ID 5745
Other Names Parathyroid hormone/parathyroid hormone-related peptide receptor, PTH/PTHrP type I receptor, PTH/PTHr receptor, Parathyroid hormone 1 receptor, PTH1 receptor, PTH1R, PTHR, PTHR1
Target/Specificity Recognizes human PTH/PTHrP receptor, MW 80kD, and the receptor dimer, Mr 160kD. A faint nonspecific band at 110kD is also detected. This antibody does not detect the PTH2 receptor.
Reconstitution & Storage Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
PrecautionsPTHR / PTHR1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PTH1R
Synonyms PTHR, PTHR1
Function Receptor for parathyroid hormone and for parathyroid hormone- related peptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system.
Cellular Location Cell membrane; Multi-pass membrane protein
Tissue Location Expressed in most tissues. Most abundant in kidney, bone and liver.
Research Areas
Citations (0)
citation

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Background

This is a receptor for parathyroid hormone and for parathyroid hormone-related peptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system.

References

Schipani E.,et al.Endocrinology 132:2157-2165(1993).
Schneider H.,et al.Eur. J. Pharmacol. 246:149-155(1993).
Schipani E.,et al.J. Clin. Endocrinol. Metab. 80:1611-1621(1995).
Levine M.A.,et al.Submitted (NOV-1994) to the EMBL/GenBank/DDBJ databases.
King M.M.,et al.Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.

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$ 467.50
Cat# ALS12187
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