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>   home   >   Products   >   Primary Antibodies   >   CREB3L4 / AIBZIP Antibody (C-Terminus)   

CREB3L4 / AIBZIP Antibody (C-Terminus)

Goat Polyclonal Antibody

     
  • WB - CREB3L4 / AIBZIP Antibody (C-Terminus) ALS12189
    Antibody staining (0.5 ug/ml) of Human Placenta lysate (RIPA buffer, 35 ug total protein per lane).
  • IHC - CREB3L4 / AIBZIP Antibody (C-Terminus) ALS12189
    Anti-CREB3L4 antibody IHC of human prostate.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q8TEY5
Reactivity Human
Host Goat
Clonality Polyclonal
Calculated MW 43kDa
Dilution ELISA (1:32000), IHC-P (2.5-5 µg/ml), WB (1:32000)
Additional Information
Gene ID 148327
Other Names Cyclic AMP-responsive element-binding protein 3-like protein 4, cAMP-responsive element-binding protein 3-like protein 4, Androgen-induced basic leucine zipper protein, AIbZIP, Attaching to CRE-like 1, ATCE1, Cyclic AMP-responsive element-binding protein 4, CREB-4, cAMP-responsive element-binding protein 4, Transcript induced in spermiogenesis protein 40, Tisp40, hJAL, Processed cyclic AMP-responsive element-binding protein 3-like protein 4, CREB3L4, AIBZIP, CREB4, JAL
Target/Specificity Human CREB3L4.
Reconstitution & Storage Store at -20°C. Minimize freezing and thawing.
PrecautionsCREB3L4 / AIBZIP Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CREB3L4
Synonyms AIBZIP, CREB4, JAL
Function Transcriptional activator that may play a role in the unfolded protein response. Binds to the UPR element (UPRE) but not to CRE element. Preferentially binds DNA with to the consensus sequence 5'-T[GT]ACGT[GA][GT]-3' and has transcriptional activation activity from UPRE. Binds to NF-kappa-B site and has transcriptional activation activity from NF-kappa-B-containing regulatory elements (By similarity).
Cellular Location Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus membrane; Single-pass type II membrane protein. Note=May also be located in Golgi apparatus
Tissue Location According to PubMed:11830526, exclusively expressed in the prostate. Expressed in breast and prostate cancer cell lines. Expressed in prostatic luminal epithelial cells (at protein level). Expression is significantly more abundant in prostate cancer than in benign prostatic tissue (prostatic hyperplasia). According to PubMed:12111373, also expressed in brain, pancreas and skeletal muscle, and at lower levels in small intestine, testis, leukocyte and thymus
Citations (0)

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Background

Transcriptional activator that may play a role in the unfolded protein response. Binds to the UPR element (UPRE) but not to CRE element. Preferentially binds DNA with to the consensus sequence 5'-T[GT]ACGT[GA][GT]-3' and has transcriptional activation activity from UPRE. Binds to NF-kappa-B site and has transcriptional activation activity from NF-kappa-B-containing regulatory elements (By similarity).

References

Qi H.,et al.Cancer Res. 62:721-733(2002).
Cao G.,et al.J. Hum. Genet. 47:373-376(2002).
Fujita K.,et al.Submitted (DEC-2000) to the EMBL/GenBank/DDBJ databases.
Guo J.H.,et al.Submitted (AUG-2001) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).

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$ 395.00
Cat# ALS12189
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