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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   CED6 / GULP1 Antibody (C-Terminus)   

CED6 / GULP1 Antibody (C-Terminus)

Goat Polyclonal Antibody

     
  • WB - CED6 / GULP1 Antibody (C-Terminus) ALS12190
    Antibody staining (0.2 ug/ml) of Human Placenta lysate (RIPA buffer, 30 ug total protein per lane).
  • IHC - CED6 / GULP1 Antibody (C-Terminus) ALS12190
    Anti-GULP1 / CED6 antibody IHC of human kidney.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q9UBP9
Reactivity Human, Mouse, Rat, Rabbit, Hamster, Monkey, Pig, Chicken, Bovine, Dog
Host Goat
Clonality Polyclonal
Calculated MW 34kDa
Dilution ELISA (1:64000), IHC-P (5 µg/ml), WB (0.2-0.6 µg/ml)
Additional Information
Gene ID 51454
Other Names PTB domain-containing engulfment adapter protein 1, Cell death protein 6 homolog, PTB domain adapter protein CED-6, Protein GULP, GULP1, CED6, GULP
Target/Specificity Human GULP1 / CED6.
Reconstitution & Storage Store at -20°C. Minimize freezing and thawing.
PrecautionsCED6 / GULP1 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GULP1
Synonyms CED6, GULP
Function May function as an adapter protein. Required for efficient phagocytosis of apoptotic cells. Modulates cellular glycosphingolipid and cholesterol transport. May play a role in the internalization and endosomal trafficking of various LRP1 ligands, such as PSAP. Increases cellular levels of GTP-bound ARF6.
Cellular Location Cytoplasm. Note=May associate with the cytoplasmic side of the plasma membrane and early endosomes
Tissue Location Widely expressed. Detected in macrophages, pancreas, kidney, skeletal muscle, heart, colon, intestine, lung, placenta and ovary.
Research Areas
Citations (0)

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Background

May function as an adapter protein. Required for efficient phagocytosis of apoptotic cells. Modulates cellular glycosphingolipid and cholesterol transport. May play a role in the internalization and endosomal trafficking of various LRP1 ligands, such as PSAP. Increases cellular levels of GTP-bound ARF6.

References

Liu Q.A.,et al.Curr. Biol. 9:1347-1350(1999).
Smits E.,et al.Curr. Biol. 9:1351-1354(1999).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 434:724-731(2005).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.

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$ 395.00
Cat# ALS12190
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