|Application ||IHC-P, E|
|Reactivity||Human, Rabbit, Hamster, Monkey|
|Dilution||ELISA (1:32000), IHC-P (5 µg/ml),|
|Other Names||Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3, AGAP-3, CRAM-associated GTPase, CRAG, Centaurin-gamma-3, Cnt-g3, MR1-interacting protein, MRIP-1, AGAP3, CENTG3|
|Target/Specificity||Human AGAP3 / CENTG3.|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||AGAP3 / CENTG3 / MRIP-1 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||GTPase-activating protein for the ADP ribosylation factor family (Potential). GTPase which may be involved in the degradation of expanded polyglutamine proteins through the ubiquitin-proteasome pathway.|
|Cellular Location||Cytoplasm. Note=In cells upon oxidative stress or in brains of Machado-Joseph disease patients, translocates to PML nuclear bodies|
|Tissue Location||Widely expressed.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
GTPase-activating protein for the ADP ribosylation factor family (Potential). GTPase which may be involved in the degradation of expanded polyglutamine proteins through the ubiquitin-proteasome pathway.
Xia C.,et al.Mol. Cell. Biol. 23:2476-2488(2003).
Hong W.,et al.Submitted (AUG-2001) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 424:157-164(2003).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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