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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   MPP5 Antibody (N-Terminus)   

MPP5 Antibody (N-Terminus)

Goat Polyclonal Antibody

     
  • IHC - MPP5 Antibody (N-Terminus) ALS12198
    Anti-MPP5 antibody IHC of human kidney.
  • IHC - MPP5 Antibody (N-Terminus) ALS12198
    Anti-MPP5 antibody IHC of human small intestine.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q8N3R9
Reactivity Human, Rabbit, Monkey, Pig, Horse, Bovine, Dog
Host Goat
Clonality Polyclonal
Calculated MW 77kDa
Dilution ELISA (1:32000), IHC-P (5 µg/ml), WB (1:32000)
Additional Information
Gene ID 64398
Other Names MAGUK p55 subfamily member 5, MPP5
Target/Specificity Human MPP5.
Reconstitution & Storage Store at -20°C. Minimize freezing and thawing.
PrecautionsMPP5 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MPP5
Function May play a role in tight junctions biogenesis and in the establishment of cell polarity in epithelial cells. May modulate SC6A1/GAT1-mediated GABA uptake by stabilizing the transporter. Required for localization of EZR to the apical membrane of parietal cells and may play a role in the dynamic remodeling of the apical cytoskeleton (By similarity).
Cellular Location Cell membrane; Peripheral membrane protein. Endomembrane system; Peripheral membrane protein. Cell junction, tight junction. Note=Localized to the tight junctions of epithelial cells and a subset of intracellular vesicles. In the retina, detected at the outer limiting membrane (OLM), apical to the adherens junction (AJ), where it colocalizes with CRB1 Colocalizes with MPP1 in the retina at the outer limiting membrane (OLM). Localized to the Purkinje cell body and axon
Tissue Location Expressed in the retina (at protein level).
Research Areas
Citations (0)

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Background

May play a role in tight junctions biogenesis and in the establishment of cell polarity in epithelial cells. May modulate SC6A1/GAT1-mediated GABA uptake by stabilizing the transporter. Required for localization of EZR to the apical membrane of parietal cells and may play a role in the dynamic remodeling of the apical cytoskeleton (By similarity).

References

Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Kantardzhieva A.,et al.Invest. Ophthalmol. Vis. Sci. 46:2192-2201(2005).
Stoehr H.,et al.J. Comp. Neurol. 481:31-41(2005).

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$ 395.00
Cat# ALS12198
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