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IFT74 / CCDC2 Antibody (C-Terminus)

Goat Polyclonal Antibody

     
  • IHC - IFT74 / CCDC2 Antibody (C-Terminus) ALS12205
    Anti-IFT74 antibody IHC of human liver.
  • SPECIFICATION
  • CITATIONS
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  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q96LB3
Reactivity Human, Monkey
Host Goat
Clonality Polyclonal
Calculated MW 69kDa
Dilution ELISA (1:16000), IHC-P (5 µg/ml),
Additional Information
Gene ID 80173
Other Names Intraflagellar transport protein 74 homolog, Capillary morphogenesis gene 1 protein, CMG-1, Coiled-coil domain-containing protein 2, IFT74, CCDC2, CMG1
Target/Specificity Human IFT74.
Reconstitution & Storage Store at -20°C. Minimize freezing and thawing.
PrecautionsIFT74 / CCDC2 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name IFT74
Synonyms CCDC2, CMG1
Function Component of the intraflagellar transport (IFT) complex B: together with IFT81, forms a tubulin-binding module that specifically mediates transport of tubulin within the cilium. Binds beta-tubulin via its basic region. Required for ciliogenesis.
Cellular Location Cell projection, cilium. Cytoplasmic vesicle. Note=Localizes along primary cilia at interphase and around the basal body/centriole at interphase and mitosis
Tissue Location Highly expressed in adult and fetal kidney and expressed at lower level in adult heart, placenta, lung, liver and pancreas, and in fetal heart, lung and liver. Little to no expression was detected in adult brain and skeletal muscle or in fetal brain, thymus and spleen.
Research Areas
Citations (0)

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Background

Component of the intraflagellar transport (IFT) complex B: together with IFT81, forms a tubulin-binding module that specifically mediates transport of tubulin within the cilium. Binds beta-tubulin via its basic region. Required for ciliogenesis.

References

Bell S.E.,et al.J. Cell Sci. 114:2755-2773(2001).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Humphray S.J.,et al.Nature 429:369-374(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Li W.B.,et al.Submitted (APR-2003) to the EMBL/GenBank/DDBJ databases.

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$ 395.00
Cat# ALS12205
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