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ARSB / Arylsulfatase B Antibody (Internal)

Goat Polyclonal Antibody

     
  • WB - ARSB / Arylsulfatase B Antibody (Internal) ALS12210
    Antibody (0.03 ug/ml) staining of Human Heart lysate (35 ug protein in RIPA buffer).
  • IHC - ARSB / Arylsulfatase B Antibody (Internal) ALS12210
    Anti-ARSB antibody IHC of human skeletal muscle.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P15848
Reactivity Human, Monkey
Host Goat
Clonality Polyclonal
Calculated MW 60kDa
Dilution ELISA (1:64000), IHC-P (5 µg/ml), WB (0.03-0.1 µg/ml)
Additional Information
Gene ID 411
Other Names Arylsulfatase B, ASB, 3.1.6.12, N-acetylgalactosamine-4-sulfatase, G4S, ARSB
Target/Specificity Human ARSB. This antibody is expected to recognise both reported isoforms (NP_000037.2; NP_942002.1).
Reconstitution & Storage Store at -20°C. Minimize freezing and thawing.
PrecautionsARSB / Arylsulfatase B Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ARSB
Function Removes sulfate groups from chondroitin-4-sulfate (C4S) and regulates its degradation (PubMed:19306108). Involved in the regulation of cell adhesion, cell migration and invasion in colonic epithelium (PubMed:19306108). In the central nervous system, is a regulator of neurite outgrowth and neuronal plasticity, acting through the control of sulfate glycosaminoglycans and neurocan levels (By similarity).
Cellular Location Lysosome. Cell surface {ECO:0000250|UniProtKB:P50429}
Research Areas
Citations (0)

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Background

Removes sulfate groups from chondroitin-4-sulfate (C4S) and regulates its degradation (PubMed:19306108). Involved in the regulation of cell adhesion, cell migration and invasion in colonic epithelium (PubMed:19306108). In the central nervous system, is a regulator of neurite outgrowth and neuronal plasticity, acting through the control of sulfate glycosaminoglycans and neurocan levels (By similarity).

References

Peters C.,et al.J. Biol. Chem. 265:3374-3381(1990).
Schuchman E.H.,et al.Genomics 6:149-158(1990).
Modaressi S.,et al.Biol. Chem. Hoppe-Seyler 374:327-335(1993).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Schmutz J.,et al.Nature 431:268-274(2004).

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$ 395.00
Cat# ALS12210
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