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CBX1 / HP1 Beta Antibody (Internal)
Goat Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | P83916 |
| Reactivity | Human, Mouse, Hamster, Monkey, Pig, Horse, Bovine, Dog |
| Host | Goat |
| Clonality | Polyclonal |
| Calculated MW | 21kDa |
| Dilution | ELISA (1:32000), IHC-P (2.5 µg/ml), WB (1:32000) |
| Gene ID | 10951 |
|---|---|
| Other Names | Chromobox protein homolog 1, HP1Hsbeta, Heterochromatin protein 1 homolog beta, HP1 beta, Heterochromatin protein p25, M31, Modifier 1 protein, p25beta, CBX1, CBX |
| Target/Specificity | Human CBX1. Variants (NP_006798.1; NP_001120700.1) encode the same protein. |
| Reconstitution & Storage | Store at -20°C. Minimize freezing and thawing. |
| Precautions | CBX1 / HP1 Beta Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CBX1 |
|---|---|
| Synonyms | CBX |
| Function | Component of heterochromatin. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane. |
| Cellular Location | Nucleus Note=Unassociated with chromosomes during mitosis |
| Tissue Location | Expressed in all adult and embryonic tissues. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Component of heterochromatin. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane.
References
Furuta K.,et al.Chromosoma 106:11-19(1997).
Lubec G.,et al.Submitted (DEC-2008) to UniProtKB.
Minc E.,et al.Chromosoma 108:220-234(1999).
Aagaard L.,et al.EMBO J. 18:1923-1938(1999).
Hughes-Davies L.,et al.Cell 115:523-535(2003).
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