|Application ||WB, IHC-P, E|
|Calculated MW||47315 Da|
|Dilution||ELISA (1:32000), IHC-P (5 µg/ml), WB (0.3-1 µg/ml)|
|Other Names||Casein kinase I isoform epsilon, CKI-epsilon, CKIe, 184.108.40.206, CSNK1E|
|Target/Specificity||Human CSNK1E. Both reported variants represent identical protein (NP_001885.1 and NP_689407.1).|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||CSNK1E / CK1 Epsilon Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates DVL1. Central component of the circadian clock. In balance with PP1, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phospohorylation. Controls PER1 and PER2 nuclear transport and degradation. Inhibits cytokine- induced granuloytic differentiation.|
|Cellular Location||Cytoplasm. Nucleus|
|Tissue Location||Expressed in all tissues examined, including brain, heart, lung, liver, pancreas, kidney, placenta and skeletal muscle. Expressed in monocytes and lymphocytes but not in granulocytes|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.