|Application ||IHC-P, ICC, E, Flo|
|Dilution||ELISA (1:75000), Flo (1-3 µg/10E6 cells), ICC (1:300), IHC-P (5 µg/ml) ,|
|Other Names||C-C chemokine receptor type 6, C-C CKR-6, CC-CKR-6, CCR-6, Chemokine receptor-like 3, CKR-L3, DRY6, G-protein coupled receptor 29, GPR-CY4, GPRCY4, LARC receptor, CD196, CCR6, CKRL3, CMKBR6, GPR29, STRL22|
|Target/Specificity||Recognizes human CCR6. Peptide sequence is <50% identical to other human chemokine receptors in this region. Species cross-reactivity: mouse.|
|Reconstitution & Storage||Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.|
|Precautions||CCR6 Antibody (aa18-46) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||CKRL3, CMKBR6, GPR29, STRL22|
|Function||Receptor for a C-C type chemokine. Binds to MIP-3- alpha/LARC and subsequently transduces a signal by increasing the intracellular calcium ions level.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||Spleen, lymph nodes, appendix, and fetal liver. Expressed in lymphocytes, T-cells and B-cells but not in natural killer cells, monocytes or granulocytes|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Receptor for a C-C type chemokine. Binds to MIP-3- alpha/LARC and subsequently transduces a signal by increasing the intracellular calcium ions level.
Baba M.,et al.J. Biol. Chem. 272:14893-14898(1997).
Lautens L.L.,et al.Submitted (APR-1996) to the EMBL/GenBank/DDBJ databases.
Zaballos A.,et al.Biochem. Biophys. Res. Commun. 227:846-853(1996).
McCoy R.,et al.Submitted (SEP-1996) to the EMBL/GenBank/DDBJ databases.
Liao F.,et al.Genomics 40:175-180(1997).
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