|Application ||WB, IHC-P, E|
|Reactivity||Human, Mouse, Rat, Hamster|
|Dilution||ELISA (1:32000), IHC-P (2.5 µg/ml), WB (1:32000)|
|Other Names||Four and a half LIM domains protein 1, FHL-1, Skeletal muscle LIM-protein 1, SLIM, SLIM-1, FHL1, SLIM1|
|Target/Specificity||Human FHL1. This antibody is expected to recognise isoforms 2( NP_001440.1) and 5 (NP_001153171.1). Since June 2009 the second N residue in the immunizing peptide is no longer representative as it has been substituted by Q at position 284 of NP_00144 ...|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||SLIM / FHL1 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May have an involvement in muscle development or hypertrophy.|
|Cellular Location||Isoform 1: Cytoplasm. Isoform 2: Nucleus. Cytoplasm, cytosol. Note=Predominantly nuclear in myoblasts but is cytosolic in differentiated myotubes|
|Tissue Location||Isoform 1 is highly expressed in skeletal muscle and to a lesser extent in heart, placenta, ovary, prostate, testis, small intestine, colon and spleen. Expression is barely detectable in brain, lung, liver, kidney, pancreas, thymus and peripheral blood leukocytes. Isoform 2 is expressed in brain, skeletal muscle and to a lesser extent in heart, colon, prostate and small intestine. Isoform 3 is expressed in testis, heart and skeletal muscle.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
May have an involvement in muscle development or hypertrophy.
Morgan M.J.,et al.Biochem. Biophys. Res. Commun. 225:632-638(1996).
Morgan M.J.,et al.Submitted (FEB-1998) to the EMBL/GenBank/DDBJ databases.
Lee S.M.Y.,et al.Gene 216:163-170(1998).
Greene W.K.,et al.Gene 232:203-207(1999).
Lee S.M.Y.,et al.Gene 237:253-263(1999).
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