|Application ||WB, IHC-P, E|
|Reactivity||Human, Rabbit, Monkey|
|Dilution||ELISA (1:128000), IHC-P (5 µg/ml), WB (1-3 µg/ml)|
|Other Names||Claudin-14, CLDN14|
|Target/Specificity||Human CLDN14 / Claudin 14. Reported variants represent identical protein (NP_036262.1; NP_652763.1; NP_001139551.1; NP_001139550.1 and NP_001139549.1).|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||CLDN14 / Claudin 14 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity.|
|Cellular Location||Cell junction, tight junction. Cell membrane; Multi-pass membrane protein|
|Tissue Location||Liver, kidney. Also found in ear.|
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Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity.
Keen T.J.,et al.Submitted (JAN-1999) to the EMBL/GenBank/DDBJ databases.
Wilcox E.R.,et al.Cell 104:165-172(2001).
Wattenhofer M.,et al.Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases.
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Hattori M.,et al.Nature 405:311-319(2000).
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