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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   SCNN1G / ENaC Gamma Antibody (C-Terminus)   

SCNN1G / ENaC Gamma Antibody (C-Terminus)

Rabbit Polyclonal Antibody

     
  • IHC - SCNN1G / ENaC Gamma Antibody (C-Terminus) ALS12343
    Anti-SCNN1G antibody IHC of human kidney.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P51170
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 74kDa
Dilution IHC-P (5 µg/ml), WB (1 µg/ml),
Additional Information
Gene ID 6340
Other Names Amiloride-sensitive sodium channel subunit gamma, Epithelial Na(+) channel subunit gamma, ENaCG, Gamma-ENaC, Gamma-NaCH, Nonvoltage-gated sodium channel 1 subunit gamma, SCNEG, SCNN1G
Target/Specificity synthetic peptide corresponding to C-terminal residues of human SCNN1G(Amiloride-sensitive sodium channel gamma-subunit)
Reconstitution & Storage +4°C or -20°C, Avoid repeated freezing and thawing.
PrecautionsSCNN1G / ENaC Gamma Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SCNN1G
Function Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.
Cellular Location Apical cell membrane; Multi- pass membrane protein {ECO:0000250|UniProtKB:P37089}. Note=Apical membrane of epithelial cells.
Tissue Location Expressed in kidney (at protein level).
Research Areas
Citations (0)

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Background

Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.

References

Voilley N.,et al.Genomics 28:560-565(1995).
McDonald F.J.,et al.Am. J. Physiol. 268:C1157-C1163(1995).
Saxena A.,et al.J. Clin. Endocrinol. Metab. 87:3344-3350(2002).
Thomas C.P.,et al.J. Biol. Chem. 271:26062-26066(1996).
Hansson J.H.,et al.Nat. Genet. 11:76-82(1995).

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$ 395.00
Cat# ALS12343
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