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HYAL1 Antibody (Internal)

Goat Polyclonal Antibody

     
  • IHC - HYAL1 Antibody (Internal) ALS12346
    Anti-HYAL1 antibody IHC of human liver.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, E
Primary Accession Q12794
Reactivity Human, Monkey, Dog
Host Goat
Clonality Polyclonal
Calculated MW 48kDa
Dilution ELISA (1:128000), IHC-P (5 µg/ml),
Additional Information
Gene ID 3373
Other Names Hyaluronidase-1, Hyal-1, 3.2.1.35, Hyaluronoglucosaminidase-1, Lung carcinoma protein 1, LuCa-1, HYAL1, LUCA1
Target/Specificity Human HYAL1. This antibody is expected to recognise isoform 1 (NP_009296.1), isoform 2 (NP_695014.1), isoform 3 (NP_695015.1) and isoform 5 (NP_695017.1). Reported variants represent identical protein (NP_009296.1; NP_149349.2; NP_695013.1).
Reconstitution & Storage Store at -20°C. Minimize freezing and thawing.
PrecautionsHYAL1 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HYAL1
Synonyms LUCA1
Function May have a role in promoting tumor progression. May block the TGFB1-enhanced cell growth.
Cellular Location Secreted. Lysosome
Tissue Location Highly expressed in the liver, kidney and heart. Weakly expressed in lung, placenta and skeletal muscle. No expression detected in adult brain. Isoform 1 is expressed only in bladder and prostate cancer cells, G2/G3 bladder tumor tissues and lymph node specimens showing tumor invasive tumors cells. Isoform 3, isoform 4, isoform 5 and isoform 6 are expressed in normal bladder and bladder tumor tissues.
Research Areas
Citations (0)

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Background

May have a role in promoting tumor progression. May block the TGFB1-enhanced cell growth.

References

Wei M.H.,et al.Cancer Res. 56:1487-1492(1996).
Frost G.I.,et al.Biochem. Biophys. Res. Commun. 236:10-15(1997).
Frost G.I.,et al.Oncogene 19:870-877(2000).
Lokeshwar V.B.,et al.J. Biol. Chem. 277:33654-33663(2002).
Forgacs E.,et al.Submitted (JUL-1999) to the EMBL/GenBank/DDBJ databases.

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$ 395.00
Cat# ALS12346
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(40 western blots)
Availability: 5 days
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