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SCN2B Antibody (N-Terminus)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | O60939 |
| Reactivity | Human, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 24kDa |
| Dilution | IHC-P (10-20 µg/ml), WB (1 µg/ml), |
| Gene ID | 6327 |
|---|---|
| Other Names | Sodium channel subunit beta-2, SCN2B |
| Target/Specificity | synthetic peptide corresponding to N-terminal residues of rat Scn2b (Sodium channel beta-2 subunit) |
| Reconstitution & Storage | +4°C or -20°C, Avoid repeated freezing and thawing. |
| Precautions | SCN2B Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SCN2B |
|---|---|
| Function | Crucial in the assembly, expression, and functional modulation of the heterotrimeric complex of the sodium channel. The subunit beta-2 causes an increase in the plasma membrane surface area and in its folding into microvilli. Interacts with TNR may play a crucial role in clustering and regulation of activity of sodium channels at nodes of Ranvier (By similarity). |
| Cellular Location | Membrane; Single-pass type I membrane protein. |
| Tissue Location | Brain specific. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Crucial in the assembly, expression, and functional modulation of the heterotrimeric complex of the sodium channel. The subunit beta-2 causes an increase in the plasma membrane surface area and in its folding into microvilli. Interacts with TNR may play a crucial role in clustering and regulation of activity of sodium channels at nodes of Ranvier (By similarity).
References
Eubanks J.,et al.NeuroReport 8:2775-2779(1997).
Bolino A.,et al.Eur. J. Hum. Genet. 6:629-634(1998).
Cruz J.S.,et al.Science 284:711-711(1999).
Isom L.L.,et al.Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases.
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
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