|Application ||WB, IHC-P, E|
|Reactivity||Human, Mouse, Rat, Rabbit, Hamster, Monkey, Pig, Chicken, Horse, Bovine, Dog|
|Dilution||ELISA (1:64000), IHC-P (5 µg/ml), WB (0.3-1 µg/ml)|
|Other Names||Mothers against decapentaplegic homolog 9, MAD homolog 9, Mothers against DPP homolog 9, Madh6, SMAD family member 9, SMAD 9, Smad9, SMAD9, MADH6, MADH9|
|Target/Specificity||Human SMAD9. This antibody is not expected to cross-react with SMAD1 and SMAD5.|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||SMAD9 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD9 is a receptor-regulated SMAD (R-SMAD).|
|Cellular Location||Cytoplasm. Nucleus. Note=In the cytoplasm in the absence of ligand Migration to the nucleus when complexed with SMAD4 (By similarity).|
|Tissue Location||Expressed in heart, brain, placenta, lung, skeletal muscle, prostate, testis, ovary and small intestine. Also expressed in fetal brain, lung and kidney|
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Provided below are standard protocols that you may find useful for product applications.
Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD9 is a receptor-regulated SMAD (R-SMAD).
Watanabe T.K.,et al.Genomics 42:446-451(1997).
Dunham A.,et al.Nature 428:522-528(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Massague J.,et al.Annu. Rev. Biochem. 67:753-791(1998).
Verschueren K.,et al.Cytokine Growth Factor Rev. 10:187-199(1999).
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