SMAD9 Antibody (Internal)
Goat Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | O15198 |
Reactivity | Human, Mouse, Rat, Rabbit, Hamster, Monkey, Pig, Chicken, Horse, Bovine, Dog |
Host | Goat |
Clonality | Polyclonal |
Calculated MW | 52kDa |
Dilution | ELISA (1:64000), IHC-P (5 µg/ml), WB (0.3-1 µg/ml) |
Gene ID | 4093 |
---|---|
Other Names | Mothers against decapentaplegic homolog 9, MAD homolog 9, Mothers against DPP homolog 9, Madh6, SMAD family member 9, SMAD 9, Smad9, SMAD9, MADH6, MADH9 |
Target/Specificity | Human SMAD9. This antibody is not expected to cross-react with SMAD1 and SMAD5. |
Reconstitution & Storage | Store at -20°C. Minimize freezing and thawing. |
Precautions | SMAD9 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | SMAD9 |
---|---|
Synonyms | MADH6, MADH9, SMAD8 {ECO:0000303|PubMed: |
Function | Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD9 is a receptor- regulated SMAD (R-SMAD). |
Cellular Location | Cytoplasm. Nucleus. Note=In the cytoplasm in the absence of ligand. Migration to the nucleus when complexed with SMAD4 (By similarity). |
Tissue Location | Expressed in heart, brain, placenta, lung, skeletal muscle, prostate, testis, ovary and small intestine. Also expressed in fetal brain, lung and kidney |
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Provided below are standard protocols that you may find useful for product applications.
Background
Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD9 is a receptor-regulated SMAD (R-SMAD).
References
Watanabe T.K.,et al.Genomics 42:446-451(1997).
Dunham A.,et al.Nature 428:522-528(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Massague J.,et al.Annu. Rev. Biochem. 67:753-791(1998).
Verschueren K.,et al.Cytokine Growth Factor Rev. 10:187-199(1999).
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