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>   home   >   Products   >   Primary Antibodies   >   Neuroscience   >   MANF / ARMET Antibody (C-Terminus)   

MANF / ARMET Antibody (C-Terminus)

Rabbit Polyclonal Antibody

     
  • WB - MANF / ARMET Antibody (C-Terminus) ALS12389
    Western blot of MANF in mouse brain tissue lysate with MANF antibody at (A) 1 and (B) 2 ug/ml.
  • IF - MANF / ARMET Antibody (C-Terminus) ALS12389
    Immunofluorescence of MANF in Human Brain cells with MANF antibody at 20 ug/ml.
  • IHC - MANF / ARMET Antibody (C-Terminus) ALS12389
    Anti-MANF / ARMET antibody IHC of human brain, cerebellum.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, E
Primary Accession P55145
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 21kDa
Dilution IHC-P (5 µg/ml), WB (1-2 µg/ml),
Additional Information
Gene ID 7873
Other Names Mesencephalic astrocyte-derived neurotrophic factor, Arginine-rich protein, Protein ARMET, MANF, ARMET, ARP
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
PrecautionsMANF / ARMET Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MANF
Synonyms ARMET, ARP
Function Selectively promotes the survival of dopaminergic neurons of the ventral mid-brain. Modulates GABAergic transmission to the dopaminergic neurons of the substantia nigra. Enhances spontaneous, as well as evoked, GABAergic inhibitory postsynaptic currents in dopaminergic neurons (By similarity). Inhibits cell proliferation and endoplasmic reticulum (ER) stress-induced cell death.
Cellular Location Secreted
Research Areas
Citations (0)

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Background

Selectively promotes the survival of dopaminergic neurons of the ventral mid-brain. Modulates GABAergic transmission to the dopaminergic neurons of the substantia nigra. Enhances spontaneous, as well as evoked, GABAergic inhibitory postsynaptic currents in dopaminergic neurons (By similarity). Inhibits cell proliferation and endoplasmic reticulum (ER) stress-induced cell death.

References

Shridhar V.,et al.Oncogene 12:1931-1939(1996).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Muzny D.M.,et al.Nature 440:1194-1198(2006).
Gevaert K.,et al.Nat. Biotechnol. 21:566-569(2003).
Petrova P.,et al.J. Mol. Neurosci. 20:173-188(2003).

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$ 395.00
Cat# ALS12389
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