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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   TNFRSF25 / DR3 Antibody (aa25-40)   

TNFRSF25 / DR3 Antibody (aa25-40)

Rabbit Polyclonal Antibody

  • IHC - TNFRSF25 / DR3 Antibody (aa25-40) ALS12405
    Anti-DR3 antibody IHC of human prostate.
  • WB - TNFRSF25 / DR3 Antibody (aa25-40) ALS12405
    Western blot of DR3 in Jurkat total cell lysate with DR3 antibody at 1:1000 dilution.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q93038
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Calculated MW 45kDa
Dilution IHC-P (10 µg/ml), WB (1:500-1:1000),
Additional Information
Gene ID 8718
Other Names Tumor necrosis factor receptor superfamily member 25, Apo-3, Apoptosis-inducing receptor AIR, Apoptosis-mediating receptor DR3, Apoptosis-mediating receptor TRAMP, Death receptor 3, Lymphocyte-associated receptor of death, LARD, Protein WSL, Protein WSL-1, TNFRSF25, APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Target/Specificity Peptide corresponding to amino acids 25 to 40 of human DR3 precursor.
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
PrecautionsTNFRSF25 / DR3 Antibody (aa25-40) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms APO3, DDR3, DR3, TNFRSF12, WSL, WSL1
Function Receptor for TNFSF12/APO3L/TWEAK. Interacts directly with the adapter TRADD. Mediates activation of NF-kappa-B and induces apoptosis. May play a role in regulating lymphocyte homeostasis.
Cellular Location Isoform 1: Cell membrane; Single-pass type I membrane protein Isoform 9: Cell membrane; Single-pass type I membrane protein Isoform 3: Secreted. Isoform 5: Secreted. Isoform 7: Secreted. Isoform 10: Secreted.
Tissue Location Abundantly expressed in thymocytes and lymphocytes. Detected in lymphocyte-rich tissues such as thymus, colon, intestine, and spleen. Also found in the prostate
Research Areas
Citations (0)

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Receptor for TNFSF12/APO3L/TWEAK. Interacts directly with the adapter TRADD. Mediates activation of NF-kappa-B and induces apoptosis. May play a role in regulating lymphocyte homeostasis.


Kitson J.,et al.Nature 384:372-375(1996).
Chinnaiyan A.M.,et al.Science 274:990-992(1996).
Degli-Esposti M.A.,et al.Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases.
Marsters S.A.,et al.Curr. Biol. 6:1669-1676(1996).
Screaton G.R.,et al.Proc. Natl. Acad. Sci. U.S.A. 94:4615-4619(1997).

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$ 395.00
Cat# ALS12405
(40 western blots)
Availability: 5 days
Bulk Size
Seasonal Special on Bulk Order
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