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DRAM1 / DRAM Antibody (N-Terminus)

Rabbit Polyclonal Antibody

     
  • IF - DRAM1 / DRAM Antibody (N-Terminus) ALS12426
    Immunofluorescence of DRAM in Human Liver cells with DRAM antibody at 20 ug/ml.
    detail
  • IHC - DRAM1 / DRAM Antibody (N-Terminus) ALS12426
    Anti-DRAM1 / DRAM antibody IHC of human prostate.
    detail
  • WB - DRAM1 / DRAM Antibody (N-Terminus) ALS12426
    Western blot of DRAM in K562 cell lysate with DRAM antibody at (A) 0.5, (B) 1 and (C) 2 ug/ml.
    detail
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, E
Primary Accession Q8N682
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 26kDa
Dilution IHC-P (3 µg/ml), WB (0.5-1 µg/ml),
Additional Information
Gene ID 55332
Other Names DNA damage-regulated autophagy modulator protein 1, Damage-regulated autophagy modulator, DRAM1, DRAM
Target/Specificity 16 amino acid peptide from near the amino terminus of human DRAM.
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
PrecautionsDRAM1 / DRAM Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DRAM1
Synonyms DRAM
Function Lysosomal modulator of autophagy that plays a central role in p53/TP53-mediated apoptosis. Not involved in p73/TP73-mediated autophagy.
Cellular Location Lysosome membrane; Multi-pass membrane protein
Research Areas
Citations (0)
citation

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Background

Lysosomal modulator of autophagy that plays a central role in p53/TP53-mediated apoptosis. Not involved in p73/TP73- mediated autophagy.

References

Ota T.,et al.Nat. Genet. 36:40-45(2004).
Scherer S.E.,et al.Nature 440:346-351(2006).
Crighton D.,et al.Cell 126:121-134(2006).
Crighton D.,et al.Cell Death Differ. 14:1071-1079(2007).

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$ 467.50
Cat# ALS12426
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