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TEM7 Antibody (Internal)

Rabbit Polyclonal Antibody

  • IF - TEM7 Antibody (Internal) ALS12427
    Immunofluorescence of TEM7 in Mouse Liver cells with TEM7 antibody at 20 ug/ml.
  • IHC - TEM7 Antibody (Internal) ALS12427
    Anti-TEM7 antibody IHC of human kidney.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8IUK5
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 56kDa
Dilution IHC-P (5 µg/ml), WB (0.5-1 µg/ml),
Additional Information
Gene ID 57125
Other Names Plexin domain-containing protein 1, Tumor endothelial marker 3, Tumor endothelial marker 7, PLXDC1, TEM3, TEM7
Target/Specificity a 16 amino acid peptide from near the center of human TEM7
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
PrecautionsTEM7 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms TEM3, TEM7
Function Plays a critical role in endothelial cell capillary morphogenesis.
Cellular Location Isoform 1: Cell membrane; Single-pass type I membrane protein. Cell junction, tight junction. Note=Localized predominantly at the tight junctions of vascular endothelial cells and to a lesser extent at the luminal surface of vascular endothelial cells Isoform 3: Secreted.
Tissue Location Detected in endothelial cells from colorectal cancer, and in endothelial cells from primary cancers of the lung, liver, pancreas, breast and brain. Not detectable in endothelial cells from normal tissue. Expressed in fibrovascular membrane with increased expression in individuals with proliferative diabetic retinopathy.
Citations (0)

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Plays a critical role in endothelial cell capillary morphogenesis.


St Croix B.,et al.Science 289:1197-1202(2000).
Carson-Walter E.B.,et al.Cancer Res. 61:6649-6655(2001).
Nanda A.,et al.Cancer Res. 64:8507-8511(2004).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Lee H.K.,et al.FEBS Lett. 580:2253-2257(2006).

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$ 395.00
Cat# ALS12427
(40 western blots)
Availability: 5 days
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