TEM7 Antibody (Internal)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, IF, E |
---|---|
Primary Accession | Q8IUK5 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 56kDa |
Dilution | IHC-P (5 µg/ml), WB (0.5-1 µg/ml), |
Gene ID | 57125 |
---|---|
Other Names | Plexin domain-containing protein 1, Tumor endothelial marker 3, Tumor endothelial marker 7, PLXDC1, TEM3, TEM7 |
Target/Specificity | a 16 amino acid peptide from near the center of human TEM7 |
Reconstitution & Storage | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted. |
Precautions | TEM7 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | PLXDC1 |
---|---|
Synonyms | TEM3, TEM7 |
Function | Plays a critical role in endothelial cell capillary morphogenesis. |
Cellular Location | Secreted [Isoform 2]: Secreted. [Isoform 4]: Cytoplasm. |
Tissue Location | Detected in urine (at protein level) (PubMed:25326458, PubMed:36213313, PubMed:37453717). Detected in endothelial cells from colorectal cancer, and in endothelial cells from primary cancers of the lung, liver, pancreas, breast and brain. Not detectable in endothelial cells from normal tissue. Expressed in fibrovascular membrane with increased expression in individuals with proliferative diabetic retinopathy. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Plays a critical role in endothelial cell capillary morphogenesis.
References
St Croix B.,et al.Science 289:1197-1202(2000).
Carson-Walter E.B.,et al.Cancer Res. 61:6649-6655(2001).
Nanda A.,et al.Cancer Res. 64:8507-8511(2004).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Lee H.K.,et al.FEBS Lett. 580:2253-2257(2006).
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