|Application ||WB, IHC-P, E|
|Reactivity||Human, Mouse, Rat, Rabbit, Hamster, Monkey, Bovine, Dog|
|Dilution||ELISA (1:32000), IHC-P (3.75 µg/ml), WB (0.1-0.5 µg/ml)|
|Other Names||Actin-related protein 2/3 complex subunit 2, Arp2/3 complex 34 kDa subunit, p34-ARC, ARPC2, ARC34|
|Target/Specificity||Human ARPC2. The reported variants NP_005722.1 and NP_690601.1 represent identical protein.|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||ARPC2 / p34-Arc Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.|
|Cellular Location||Cytoplasm, cytoskeleton. Cell projection. Cell junction, synapse, synaptosome|
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Provided below are standard protocols that you may find useful for product applications.
Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.
Welch M.D.,et al.J. Cell Biol. 138:375-384(1997).
Couch F.J.,et al.Genomics 36:86-99(1996).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Gevaert K.,et al.Nat. Biotechnol. 21:566-569(2003).
Zhang C.,et al.Submitted (DEC-1998) to the EMBL/GenBank/DDBJ databases.
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