ENPEP / Aminopeptidase A Antibody (Internal)
Goat Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | Q07075 |
Reactivity | Human, Mouse, Rat, Monkey, Bovine |
Host | Goat |
Clonality | Polyclonal |
Calculated MW | 109kDa |
Dilution | ELISA (1:64000), IHC-P (3.75 µg/ml), WB (1-3 µg/ml) |
Gene ID | 2028 |
---|---|
Other Names | Glutamyl aminopeptidase, EAP, 3.4.11.7, Aminopeptidase A, AP-A, Differentiation antigen gp160, CD249, ENPEP |
Target/Specificity | Human ENPEP. |
Reconstitution & Storage | Store at -20°C. Minimize freezing and thawing. |
Precautions | ENPEP / Aminopeptidase A Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ENPEP |
---|---|
Function | Regulates central hypertension through its calcium-modulated preference to cleave N-terminal acidic residues from peptides such as angiotensin II. |
Cellular Location | Cell membrane; Single-pass type II membrane protein |
Tissue Location | Expressed in choriocarcinoma cancer cell lines (at protein level) (PubMed:10692253). Expressed by epithelial cells of the proximal tubule cells and the glomerulus of the nephron. Also found in a variety of other tissues. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Appears to have a role in the catabolic pathway of the renin-angiotensin system. Probably plays a role in regulating growth and differentiation of early B-lineage cells.
References
Nanus D.M.,et al.Proc. Natl. Acad. Sci. U.S.A. 90:7069-7073(1993).
Li L.,et al.Genomics 17:657-664(1993).
Hillier L.W.,et al.Nature 434:724-731(2005).
Liu T.,et al.J. Proteome Res. 4:2070-2080(2005).
Chen R.,et al.J. Proteome Res. 8:651-661(2009).
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