|Application ||IHC-P, E|
|Dilution||ELISA (1:64000), IHC-P (3.75 µg/ml),|
|Other Names||Membrane primary amine oxidase, 18.104.22.168, Copper amine oxidase, HPAO, Semicarbazide-sensitive amine oxidase, SSAO, Vascular adhesion protein 1, VAP-1, AOC3, VAP1|
|Target/Specificity||Human AOC3 / VAP-1.|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||AOC3 / VAP-1 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Cell adhesion protein that participates in lymphocyte extravasation and recirculation by mediating the binding of lymphocytes to peripheral lymph node vascular endothelial cells in an L-selectin-independent fashion. Has semicarbazide-sensitive (SSAO) monoamine oxidase activity. May play a role in adipogenesis.|
|Cellular Location||Cell membrane; Single-pass type II membrane protein|
|Tissue Location||Strongly expressed on the high endothelial venules of peripheral lymph nodes and on hepatic endothelia. Also highly expressed in appendix, lung and small intestine. Expressed also in adipose tissue, in bone marrow, colon, heart, kidney, ovary, pancreas, placenta, prostate, skeletal muscle, spleen and testis. Isoform 2 seems to be the predominant transcript in fetal kidneys, fetal cartilage and fetal tonsils. The highest relative expression of isoform 2 occurs in skeletal muscle, heart, pancreas, kidney, and lung.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Cell adhesion protein that participates in lymphocyte extravasation and recirculation by mediating the binding of lymphocytes to peripheral lymph node vascular endothelial cells in an L-selectin-independent fashion. Has semicarbazide-sensitive (SSAO) monoamine oxidase activity. May play a role in adipogenesis.
Zhang X.,et al.Gene 179:279-286(1996).
Smith D.J.,et al.J. Exp. Med. 188:17-27(1998).
Zhang Q.,et al.Gene 318:45-53(2003).
Kaitaniemi S.,et al.PLoS ONE 8:E54151-E54151(2013).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.