|Application ||WB, IHC-P, E|
|Dilution||ELISA (1:16000), IHC-P (3.75 µg/ml), WB (0.3-1 µg/ml)|
|Other Names||Alpha-2-antiplasmin, Alpha-2-AP, Alpha-2-plasmin inhibitor, Alpha-2-PI, Serpin F2, SERPINF2, AAP, PLI|
|Target/Specificity||Human SERPINF2 / Alpha-2-Antiplasmin. This antibody is expected to recognise both reported isoforms (NP_000925.2; NP_001159393.1). Reported variants represent identical protein (NP_000925.2; NP_001159392.1).|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||SERPINF2 / Alpha-2-Antiplasmin Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Serine protease inhibitor. The major targets of this inhibitor are plasmin and trypsin, but it also inactivates matriptase-3/TMPRSS7 and chymotrypsin.|
|Tissue Location||Expressed by the liver and secreted in plasma.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Serine protease inhibitor. The major targets of this inhibitor are plasmin and trypsin, but it also inactivates matriptase-3/TMPRSS7 and chymotrypsin.
Tone M.,et al.J. Biochem. 102:1033-1041(1987).
Hirosawa S.,et al.Proc. Natl. Acad. Sci. U.S.A. 85:6836-6840(1988).
Hirosawa S.,et al.Proc. Natl. Acad. Sci. U.S.A. 86:1612-1613(1989).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Zody M.C.,et al.Nature 440:1045-1049(2006).
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