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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   CXCL4 / PF4 Antibody   

CXCL4 / PF4 Antibody

Sheep Polyclonal Antibody

     
  • IHC - CXCL4 / PF4 Antibody ALS12466
    Anti-PF4 antibody IHC of human placenta.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, E
Primary Accession P02776
Reactivity Human
Host Sheep
Clonality Polyclonal
Calculated MW 11kDa
Dilution IHC-P (5 µg/ml)
Additional Information
Gene ID 5196
Other Names Platelet factor 4, PF-4, C-X-C motif chemokine 4, Iroplact, Oncostatin-A, Platelet factor 4, short form, PF4, CXCL4, SCYB4
Target/Specificity Recognizes human PF4.
Reconstitution & Storage +4°C or -20°C, Avoid repeated freezing and thawing.
PrecautionsCXCL4 / PF4 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PF4
Synonyms CXCL4, SCYB4
Function Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation, the short form is a more potent inhibitor than the longer form.
Cellular Location Secreted.
Research Areas
Citations (0)

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Background

Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation, the short form is a more potent inhibitor than the longer form.

References

Poncz M.,et al.Blood 69:219-223(1987).
Eisman R.,et al.Blood 76:336-344(1990).
Zhang C.,et al.Blood 98:610-617(2001).
Ebert L.,et al.Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases.
Hillier L.W.,et al.Nature 434:724-731(2005).

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$ 395.00
Cat# ALS12466
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