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LAP1 / LRRC7 Antibody (N-Terminus)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | Q96NW7 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 173kDa |
| Dilution | ELISA (1 µg/ml), IHC-P (5 µg/ml), WB (1 µg/ml) |
| Other Names | Leucine-rich repeat-containing protein 7, Densin-180, Densin, Protein LAP1, LRRC7, KIAA1365, LAP1 |
|---|---|
| Target/Specificity | synthetic peptide corresponding to N-terminal residues of human LRRC7(Leucine-rich repeat-containing protein 7) |
| Reconstitution & Storage | +4°C or -20°C, Avoid repeated freezing and thawing. |
| Precautions | LAP1 / LRRC7 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | LRRC7 |
|---|---|
| Synonyms | KIAA1365, LAP1 |
| Function | Required for normal synaptic spine architecture and function. Necessary for DISC1 and GRM5 localization to postsynaptic density complexes and for both N-methyl D-aspartate receptor-dependent and metabotropic glutamate receptor-dependent long term depression. |
| Cellular Location | Cytoplasm. Postsynaptic density |
| Tissue Location | Brain-specific. Isoform 3 is ubiquitously expressed. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Required for normal synaptic spine architecture and function. Necessary for DISC1 and GRM5 localization to postsynaptic density complexes and for both N-methyl D-aspartate receptor-dependent and metabotropic glutamate receptor-dependent long term depression.
References
Izawa I.,et al.J. Biol. Chem. 277:5345-5350(2002).
Wang L.,et al.Int. J. Mol. Med. 11:257-260(2003).
Gregory S.G.,et al.Nature 441:315-321(2006).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Nagase T.,et al.DNA Res. 7:65-73(2000).
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