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CXCR5 Antibody

Rabbit Polyclonal Antibody

     
  • IHC - CXCR5 Antibody ALS12496
    Anti-CXCR5 antibody IHC of human spleen.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P
Primary Accession P32302
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 42kDa
Dilution IHC-P (5 µg/ml)
Additional Information
Gene ID 643
Other Names C-X-C chemokine receptor type 5, CXC-R5, CXCR-5, Burkitt lymphoma receptor 1, Monocyte-derived receptor 15, MDR-15, CD185, CXCR5, BLR1, MDR15
Target/Specificity The antibody recognizes 36 kD CXCR5 of human origin. Reactivity to other species has not been tested.
Reconstitution & Storage Long term: -70°C; Short term: -20°C; Avoid freeze-thaw cycles.
PrecautionsCXCR5 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CXCR5
Synonyms BLR1, MDR15
Function Cytokine receptor that binds to B-lymphocyte chemoattractant (BLC). Involved in B-cell migration into B-cell follicles of spleen and Peyer patches but not into those of mesenteric or peripheral lymph nodes. May have a regulatory function in Burkitt lymphoma (BL) lymphomagenesis and/or B-cell differentiation.
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Expression in mature B-cells and Burkitt lymphoma cells
Research Areas
Citations (0)

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Background

Cytokine receptor that binds to B-lymphocyte chemoattractant (BLC). Involved in B-cell migration into B-cell follicles of spleen and Peyer patches but not into those of mesenteric or peripheral lymph nodes. May have a regulatory function in Burkitt lymphoma (BL) lymphomagenesis and/or B-cell differentiation.

References

Dobner T.,et al.Eur. J. Immunol. 22:2795-2799(1992).
Barella L.,et al.Biochem. J. 309:773-779(1995).
Legler D.F.,et al.J. Exp. Med. 187:655-660(1998).
Sjoeblom T.,et al.Science 314:268-274(2006).

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$ 395.00
Cat# ALS12496
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