|Application ||WB, IHC-P|
|Dilution||IHC-P (5 µg/ml)|
|Other Names||C-X-C chemokine receptor type 5, CXC-R5, CXCR-5, Burkitt lymphoma receptor 1, Monocyte-derived receptor 15, MDR-15, CD185, CXCR5, BLR1, MDR15|
|Target/Specificity||The antibody recognizes 36 kD CXCR5 of human origin. Reactivity to other species has not been tested.|
|Reconstitution & Storage||Long term: -70°C; Short term: -20°C; Avoid freeze-thaw cycles.|
|Precautions||CXCR5 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Cytokine receptor that binds to B-lymphocyte chemoattractant (BLC). Involved in B-cell migration into B-cell follicles of spleen and Peyer patches but not into those of mesenteric or peripheral lymph nodes. May have a regulatory function in Burkitt lymphoma (BL) lymphomagenesis and/or B-cell differentiation.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||Expression in mature B-cells and Burkitt lymphoma cells|
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Provided below are standard protocols that you may find useful for product applications.
Cytokine receptor that binds to B-lymphocyte chemoattractant (BLC). Involved in B-cell migration into B-cell follicles of spleen and Peyer patches but not into those of mesenteric or peripheral lymph nodes. May have a regulatory function in Burkitt lymphoma (BL) lymphomagenesis and/or B-cell differentiation.
Dobner T.,et al.Eur. J. Immunol. 22:2795-2799(1992).
Barella L.,et al.Biochem. J. 309:773-779(1995).
Legler D.F.,et al.J. Exp. Med. 187:655-660(1998).
Sjoeblom T.,et al.Science 314:268-274(2006).
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