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PLP1 / Myelin PLP Antibody (C-Terminus, clone plpc1)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, IHC-Fr |
|---|---|
| Primary Accession | P60201 |
| Reactivity | Human, Bovine |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Names | plpc1 |
| Calculated MW | 30kDa |
| Dilution | IHC-P (10 µg/ml) |
| Gene ID | 5354 |
|---|---|
| Other Names | Myelin proteolipid protein, PLP, Lipophilin, PLP1, PLP |
| Target/Specificity | Recognizes myelin proteolipid protein (PLP) in many mammalian species. This Recognizes DM20. PLP encodes the major protein components of compact CNS myelin and mutations in the PLP gene can lead to severe dysmyelinating disease |
| Reconstitution & Storage | +4°C or -20°C, Avoid repeated freezing and thawing. Store undiluted. |
| Precautions | PLP1 / Myelin PLP Antibody (C-Terminus, clone plpc1) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PLP1 |
|---|---|
| Synonyms | PLP |
| Function | This is the major myelin protein from the central nervous system. It plays an important role in the formation or maintenance of the multilamellar structure of myelin. |
| Cellular Location | Cell membrane; Multi-pass membrane protein. Myelin membrane. Note=Colocalizes with SIRT2 in internodal regions, at paranodal axoglial junction and Schmidt-Lanterman incisures of myelin sheat. |
| Volume | 50 µl |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This is the major myelin protein from the central nervous system. It plays an important role in the formation or maintenance of the multilamellar structure of myelin.
References
Diehl H.-J.,et al.Proc. Natl. Acad. Sci. U.S.A. 83:9807-9811(1986).
Simons R.,et al.Biochem. Biophys. Res. Commun. 146:666-671(1987).
Hudson L.D.,et al.Proc. Natl. Acad. Sci. U.S.A. 86:8128-8131(1989).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Ross M.T.,et al.Nature 434:325-337(2005).
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