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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   HSP90B1 / GP96 / GRP94 Antibody (aa676-803, clone 2H3)   

HSP90B1 / GP96 / GRP94 Antibody (aa676-803, clone 2H3)

Mouse Monoclonal Antibody

     
  • IHC - HSP90B1 / GP96 / GRP94 Antibody (aa676-803, clone 2H3) ALS12545
    Anti-HSP90B1 / GRP94 antibody IHC of human breast.
  • IHC - HSP90B1 / GP96 / GRP94 Antibody (aa676-803, clone 2H3) ALS12545
    Anti-HSP90B1 / GRP94 antibody IHC of human heart.
  • IHC - HSP90B1 / GP96 / GRP94 Antibody (aa676-803, clone 2H3) ALS12545
    Anti-HSP90B1 / GRP94 antibody IHC of human prostate.
  • IF - HSP90B1 / GP96 / GRP94 Antibody (aa676-803, clone 2H3) ALS12545
    Immunofluorescence staining of human ES cell colony with monoclonal anti-human TRA1 antibody (2H3).
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, E
Primary Accession P14625
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 2H3
Calculated MW 92kDa
Dilution IF (1:100-1:200), IHC-P (5 µg/ml),
Additional Information
Gene ID 7184
Other Names Endoplasmin, 94 kDa glucose-regulated protein, GRP-94, Heat shock protein 90 kDa beta member 1, Tumor rejection antigen 1, gp96 homolog, HSP90B1, GRP94, TRA1
Reconstitution & Storage Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles.
PrecautionsHSP90B1 / GP96 / GRP94 Antibody (aa676-803, clone 2H3) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HSP90B1
Synonyms GRP94, TRA1
Function Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors (By similarity). Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity.
Cellular Location Endoplasmic reticulum lumen. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV
Research Areas
Citations (0)

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Background

Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors (By similarity). Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity.

References

Maki R.G.,et al.Proc. Natl. Acad. Sci. U.S.A. 87:5658-5662(1990).
Chang S.C.,et al.Mol. Cell. Biol. 9:2153-2162(1989).
Meng S.,et al.Submitted (JUN-2001) to the EMBL/GenBank/DDBJ databases.
Gevaert K.,et al.Nat. Biotechnol. 21:566-569(2003).
Meunier L.,et al.Mol. Biol. Cell 13:4456-4469(2002).

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$ 395.00
Cat# ALS12545
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