|Application ||WB, IHC-P, E|
|Calculated MW||16838 Da|
|Dilution||IHC-P (10 µg/ml), WB (1:500-1:1000),|
|Other Names||Calmodulin, CaM, CALM1, CALM, CAM, CAM1|
|Reconstitution & Storage||Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles.|
|Precautions||Calmodulin Antibody (aa1-149, clone J4D8) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||CALM, CAM, CAM1|
|Function||Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis.|
|Cellular Location||Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Note=Distributed throughout the cell during interphase, but during mitosis becomes dramatically localized to the spindle poles and the spindle microtubules|
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