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ACOT11 / THEA Antibody (aa19-250, clone J4B2)

Mouse Monoclonal Antibody

     
  • IHC - ACOT11 / THEA Antibody (aa19-250, clone J4B2) ALS12576
    Anti-ACOT11 antibody IHC of human small intestine.
    detail
  • IHC - ACOT11 / THEA Antibody (aa19-250, clone J4B2) ALS12576
    Anti-ACOT11 antibody IHC of human spleen.
    detail
  • WB - ACOT11 / THEA Antibody (aa19-250, clone J4B2) ALS12576
    Cell lysates of LNCap, Hep3B (30 ug) were resolved by SDS-PAGE, transferred to NC membrane and...
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q8WXI4
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names J4B2
Calculated MW 68kDa
Dilution IHC-P (5 µg/ml), WB (1:500-1:1000),
Additional Information
Gene ID 26027
Other Names Acyl-coenzyme A thioesterase 11, Acyl-CoA thioesterase 11, 3.1.2.-, Acyl-CoA thioester hydrolase 11, Adipose-associated thioesterase, Brown fat-inducible thioesterase, BFIT, ACOT11, BFIT, KIAA0707, THEA
Reconstitution & Storage Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles.
PrecautionsACOT11 / THEA Antibody (aa19-250, clone J4B2) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ACOT11
Synonyms BFIT, KIAA0707, THEA
Function Has an acyl-CoA thioesterase activity with a preference for the long chain fatty acyl-CoA thioesters hexadecanoyl-CoA/palmitoyl-CoA and tetradecanoyl-CoA/myristoyl-CoA which are the main substrates in the mitochondrial beta-oxidation pathway.
Cellular Location Mitochondrion matrix. Cytoplasm
Tissue Location Isoform 1 is predominantly expressed in skeletal muscle, liver, testis, stomach, spleen, lung and brain. Isoform 2 is predominantly expressed in kidney, uterus, hibernoma and white adipose tissue
Research Areas
Citations (0)
citation

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Background

Has acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) fatty acyl-CoA substrates.

References

Adams S.H.,et al.Biochem. J. 360:135-142(2001).
Ishikawa K.,et al.DNA Res. 5:169-176(1998).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Totoki Y.,et al.Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
Gregory S.G.,et al.Nature 441:315-321(2006).

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Discontinued
Cat# ALS12576
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