|Application ||WB, IHC-P, E|
|Dilution||IHC-P (5 µg/ml), WB (1:1000-1:3000),|
|Other Names||Ubiquitin/ISG15-conjugating enzyme E2 L6, 22.214.171.124, Retinoic acid-induced gene B protein, RIG-B, UbcH8, Ubiquitin carrier protein L6, Ubiquitin-protein ligase L6, UBE2L6, UBCH8|
|Reconstitution & Storage||Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles.|
|Precautions||UBE2L6 Antibody (aa1-152, clone K1H3) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the covalent attachment of ubiquitin or ISG15 to other proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Promotes ubiquitination and subsequent proteasomal degradation of FLT3.|
|Tissue Location||Present in natural killer cells (at protein level).|
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Catalyzes the covalent attachment of ubiquitin or ISG15 to other proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Promotes ubiquitination and subsequent proteasomal degradation of FLT3.
Ardley H.C.,et al.Cytogenet. Cell Genet. 89:137-140(2000).
Liu T.,et al.Submitted (APR-1998) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Totoki Y.,et al.Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
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