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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   CHGA / Chromogranin A Antibody (aa19-131, clone 3A5)   

CHGA / Chromogranin A Antibody (aa19-131, clone 3A5)

Mouse Monoclonal Antibody

  • IHC - CHGA / Chromogranin A Antibody (aa19-131, clone 3A5) ALS12579
    Anti-CHGA / Chromogranin A antibody IHC of human adrenal.
  • IHC - CHGA / Chromogranin A Antibody (aa19-131, clone 3A5) ALS12579
    Anti-CHGA / Chromogranin A antibody IHC of human colon.
  • WB - CHGA / Chromogranin A Antibody (aa19-131, clone 3A5) ALS12579
    Cell lysates of A549, 293T and mouse kidney (35 ug) were resolved by SDS-PAGE, transferred to NC...
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P10645
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 3A5
Calculated MW 51kDa
Dilution IHC-P (5 µg/ml), WB (1:500-1:1000),
Additional Information
Gene ID 1113
Other Names Chromogranin-A, CgA, Pituitary secretory protein I, SP-I, Vasostatin-1, Vasostatin I, Vasostatin-2, Vasostatin II, EA-92, ES-43, Pancreastatin, SS-18, WA-8, WE-14, LF-19, AL-11, GV-19, GR-44, ER-37, CHGA
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
PrecautionsCHGA / Chromogranin A Antibody (aa19-131, clone 3A5) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Pancreastatin: Strongly inhibits glucose induced insulin release from the pancreas. Serpinin: Regulates granule biogenesis in endocrine cells by up-regulating the transcription of protease nexin 1 (SERPINE2) via a cAMP-PKA-SP1 pathway. This leads to inhibition of granule protein degradation in the Golgi complex which in turn promotes granule formation.
Cellular Location Cytoplasmic vesicle, secretory vesicle lumen. Cytoplasmic vesicle, secretory vesicle membrane. Secreted. Note=Associated with the secretory granule membrane through direct interaction to SCG3 that in turn binds to cholesterol-enriched lipid rafts in intragranular conditions.
Tissue Location GE-25 is found in the brain.
Research Areas
Citations (0)

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Pancreastatin strongly inhibits glucose induced insulin release from the pancreas.


Konecki D.S.,et al.J. Biol. Chem. 262:17026-17030(1987).
Helman L.J.,et al.J. Biol. Chem. 263:11559-11563(1988).
Mouland A.J.,et al.J. Biol. Chem. 269:6918-6926(1994).
Mouland A.J.,et al.Submitted (JUL-1999) to the EMBL/GenBank/DDBJ databases.
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.

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$ 395.00
Cat# ALS12579
(40 western blots)
Availability: 5 days
Bulk Size
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