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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   KLF4 Antibody (aa1-170, clone AT4E6)   

KLF4 Antibody (aa1-170, clone AT4E6)

Mouse Monoclonal Antibody

     
  • IHC - KLF4 Antibody (aa1-170, clone AT4E6) ALS12580
    Anti-KLF4 antibody IHC of human small intestine.
  • IHC - KLF4 Antibody (aa1-170, clone AT4E6) ALS12580
    Anti-KLF4 antibody IHC of human uterus.
  • WB - KLF4 Antibody (aa1-170, clone AT4E6) ALS12580
    Cell lysates of HeLa and A549 (40 ug) were resolved by SDS-PAGE, transferred to NC membrane and...
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession O43474
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names AT4E6
Calculated MW 55kDa
Dilution IHC-P (20 µg/ml), WB (1:1000-1:2000),
Additional Information
Gene ID 9314
Other Names Krueppel-like factor 4, Epithelial zinc finger protein EZF, Gut-enriched krueppel-like factor, KLF4, EZF, GKLF
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
PrecautionsKLF4 Antibody (aa1-170, clone AT4E6) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KLF4
Synonyms EZF, GKLF
Function Transcription factor; can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Contributes to the down-regulation of p53/TP53 transcription.
Cellular Location Nucleus.
Research Areas
Citations (0)

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Background

Transcription factor; can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Contributes to the down-regulation of p53/TP53 transcription.

References

Yet S.-F.,et al.J. Biol. Chem. 273:1026-1031(1998).
Foster K.W.,et al.Cell Growth Differ. 10:423-434(1999).
Camacho-Vanegas O.,et al.FASEB J. 27:432-436(2013).
Garrett-Sinha L.A.,et al.Submitted (SEP-1996) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).

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$ 395.00
Cat# ALS12580
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