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RBP4 Antibody (aa19-201, clone AT2B4)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | P02753 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Names | AT2B4 |
| Calculated MW | 23kDa |
| Dilution | IHC-P (10 µg/ml), WB (1:500-1:1000), |
| Gene ID | 5950 |
|---|---|
| Other Names | Retinol-binding protein 4, Plasma retinol-binding protein, PRBP, RBP, Plasma retinol-binding protein(1-182), Plasma retinol-binding protein(1-181), Plasma retinol-binding protein(1-179), Plasma retinol-binding protein(1-176), RBP4 |
| Reconstitution & Storage | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. |
| Precautions | RBP4 Antibody (aa19-201, clone AT2B4) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | RBP4 |
|---|---|
| Function | Retinol-binding protein that mediates retinol transport in blood plasma (PubMed:5541771). Delivers retinol from the liver stores to the peripheral tissues (Probable). Transfers the bound all-trans retinol to STRA6, that then facilitates retinol transport across the cell membrane (PubMed:22665496). |
| Cellular Location | Secreted |
| Tissue Location | Detected in blood plasma and in urine (at protein level). |
| Volume | 50 µl |
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Provided below are standard protocols that you may find useful for product applications.
Background
Delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin, this prevents its loss by filtration through the kidney glomeruli.
References
Colantuoni V.,et al.Nucleic Acids Res. 11:7769-7776(1983).
Deloukas P.,et al.Nature 429:375-381(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
D'Onofrio C.,et al.EMBO J. 4:1981-1989(1985).
Rask L.,et al.Ups. J. Med. Sci. 92:115-146(1987).
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