|Dilution||IHC-P (10 µg/ml)|
|Other Names||Coagulation factor VIII, Antihemophilic factor, AHF, Procoagulant component, Factor VIIIa heavy chain, 200 kDa isoform, Factor VIIIa heavy chain, 92 kDa isoform, Factor VIII B chain, Factor VIIIa light chain, F8, F8C|
|Target/Specificity||Recognizes full-length human Factor VIII. Does not cross-react with von Willebrand factor.|
|Reconstitution & Storage||Store at -20C or -70C. Aliquot to avoid freeze/thaw cycles.|
|Precautions||F8 / FVIII / Factor VIII Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Factor VIII, along with calcium and phospholipid, acts as a cofactor for F9/factor IXa when it converts F10/factor X to the activated form, factor Xa.|
|Cellular Location||Secreted, extracellular space.|
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Provided below are standard protocols that you may find useful for product applications.
Factor VIII, along with calcium and phospholipid, acts as a cofactor for factor IXa when it converts factor X to the activated form, factor Xa.
Truett M.A.,et al.DNA 4:333-349(1985).
Wood W.I.,et al.Nature 312:330-337(1984).
Levinson B.,et al.Genomics 14:585-589(1992).
Toole J.J.,et al.Nature 312:342-347(1984).
Gitschier J.,et al.Hum. Mol. Genet. 1:199-200(1992).
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