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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   LASS5 Antibody (C-Terminus)   

LASS5 Antibody (C-Terminus)

Rabbit Polyclonal Antibody

     
  • IF - LASS5 Antibody (C-Terminus) ALS12658
    Immunofluorescence of LASS5 in human brain tissue with LASS5 antibody at 20 ug/ml.
  • IF - LASS5 Antibody (C-Terminus) ALS12658
    Immunofluorescence of LASS5 in Human Brain cells with LASS5 antibody at 20 ug/ml.
  • WB - LASS5 Antibody (C-Terminus) ALS12658
    Western blot of LASS5 in SK-N-SH lysate with LASS5 antibody at 1 ug/ml in the (A) absence and...
  • IHC - LASS5 Antibody (C-Terminus) ALS12658
    Anti-LASS5 antibody IHC of human small intestine.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, E
Primary Accession Q8N5B7
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 46kDa
Dilution IHC-P (5 µg/ml), WB (1-2 µg/ml),
Additional Information
Gene ID 91012
Other Names Ceramide synthase 5, CerS5, 2.3.1.24, LAG1 longevity assurance homolog 5, CERS5, LASS5
Target/Specificity Multiple isoforms of LASS5 are known to exist. This antibody may cross-react with the highly homologous LASS6.
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
PrecautionsLASS5 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CERS5
Synonyms LASS5
Function Dihydroceramide synthase. Catalyzes the acylation of sphingosine to form dihydroceramide, with high selectivity toward palmitoyl-CoA as acyl donor compared to stearoyl-CoA. Inhibited by fumonisin B1 (By similarity).
Cellular Location Nucleus membrane {ECO:0000255|PROSITE- ProRule:PRU00108}; Multi-pass membrane protein Endoplasmic reticulum membrane; Multi-pass membrane protein
Research Areas
Citations (0)

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Background

Dihydroceramide synthase. Catalyzes the acylation of sphingosine to form dihydroceramide, with high selectivity toward palmitoyl-CoA as acyl donor compared to stearoyl-CoA. Inhibited by fumonisin B1 (By similarity).

References

Ota T.,et al.Nat. Genet. 36:40-45(2004).
Scherer S.E.,et al.Nature 440:346-351(2006).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.

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$ 395.00
Cat# ALS12658
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