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SLITRK1 Antibody (C-Terminus)

Rabbit Polyclonal Antibody

     
  • WB - SLITRK1 Antibody (C-Terminus) ALS12696
    Western blot of Slitrk1 in human brain tissue lysate with Slitrk1 antibody at (A) 1 and (B) 2 ug/ml.
    detail
  • IF - SLITRK1 Antibody (C-Terminus) ALS12696
    Immunofluorescence of slitrk1 in human brain tissue with slitrk1 antibody at 20 ug/ml.
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, E
Primary Accession Q96PX8
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 78kDa
Dilution IHC-P (5 µg/ml), WB (1-2 µg/ml),
Additional Information
Gene ID 114798
Other Names SLIT and NTRK-like protein 1, Leucine-rich repeat-containing protein 12, SLITRK1, KIAA1910, LRRC12
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
PrecautionsSLITRK1 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SLITRK1
Synonyms KIAA1910, LRRC12
Function It is involved in synaptogenesis and promotes excitatory synapse differentiation (PubMed:27273464, PubMed:27812321). Enhances neuronal dendrite outgrowth (PubMed:16224024, PubMed:19640509).
Cellular Location Membrane; Single-pass type I membrane protein. Secreted Synapse {ECO:0000250|UniProtKB:Q810C1}
Tissue Location Expressed predominantly in the frontal lobe of the cerebral cortex of the brain. Also expressed in some astrocytic brain tumors such as astrocytomas, oligodendrogliomas, glioblastomas, gangliogliomas and primitive neuroectodermal tumors
Research Areas
Citations (0)
citation

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Background

Enhances neuronal dendrite outgrowth.

References

Nagase T.,et al.DNA Res. 8:179-187(2001).
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Dunham A.,et al.Nature 428:522-528(2004).
Aruga J.,et al.Gene 315:87-94(2003).
Abelson J.F.,et al.Science 310:317-320(2005).

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Discontinued
Cat# ALS12696
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