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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   BAP / SIL1 Antibody (C-Terminus)   

BAP / SIL1 Antibody (C-Terminus)

Goat Polyclonal Antibody

     
  • IHC - BAP / SIL1 Antibody (C-Terminus) ALS12746
    Anti-SIL1 antibody IHC of human liver.
  • IHC - BAP / SIL1 Antibody (C-Terminus) ALS12746
    Anti-SIL1 antibody IHC of human testis.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q9H173
Reactivity Human
Host Goat
Clonality Polyclonal
Calculated MW 52kDa
Dilution ELISA (1:8000), IHC-P (5 µg/ml), WB (1-2 µg/ml)
Additional Information
Gene ID 64374
Other Names Nucleotide exchange factor SIL1, BiP-associated protein, BAP, SIL1
Target/Specificity Human SIL1. Variants (NP_071909.1; NP_001032722.1) encode the same isoform.
Reconstitution & Storage Store at -20°C. Minimize freezing and thawing.
PrecautionsBAP / SIL1 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SIL1
Function Required for protein translocation and folding in the endoplasmic reticulum (ER). Functions as a nucleotide exchange factor for the ER lumenal chaperone HSPA5.
Cellular Location Endoplasmic reticulum lumen
Tissue Location Highly expressed in tissues which produce large amounts of secreted proteins such as kidney, liver and placenta. Also expressed in colon, heart, lung, ovary, pancreas, peripheral leukocyte, prostate, spleen and thymus. Expressed at low levels throughout the brain.
Research Areas
Citations (0)

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Background

Required for protein translocation and folding in the endoplasmic reticulum (ER). Functions as a nucleotide exchange factor for the ER lumenal chaperone HSPA5.

References

Tyson J.R.,et al.EMBO J. 19:6440-6452(2000).
Chung K.T.,et al.J. Biol. Chem. 277:47557-47563(2002).
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Otsuki T.,et al.DNA Res. 12:117-126(2005).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.

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$ 395.00
Cat# ALS12746
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