|Application ||WB, IHC-P, E|
|Dilution||ELISA (1:8000), IHC-P (5 µg/ml), WB (1-2 µg/ml)|
|Other Names||Nucleotide exchange factor SIL1, BiP-associated protein, BAP, SIL1|
|Target/Specificity||Human SIL1. Variants (NP_071909.1; NP_001032722.1) encode the same isoform.|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||BAP / SIL1 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Required for protein translocation and folding in the endoplasmic reticulum (ER). Functions as a nucleotide exchange factor for the ER lumenal chaperone HSPA5.|
|Cellular Location||Endoplasmic reticulum lumen|
|Tissue Location||Highly expressed in tissues which produce large amounts of secreted proteins such as kidney, liver and placenta. Also expressed in colon, heart, lung, ovary, pancreas, peripheral leukocyte, prostate, spleen and thymus. Expressed at low levels throughout the brain.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Required for protein translocation and folding in the endoplasmic reticulum (ER). Functions as a nucleotide exchange factor for the ER lumenal chaperone HSPA5.
Tyson J.R.,et al.EMBO J. 19:6440-6452(2000).
Chung K.T.,et al.J. Biol. Chem. 277:47557-47563(2002).
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Otsuki T.,et al.DNA Res. 12:117-126(2005).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.