|Dilution||IHC-P (5 µg/ml)|
|Other Names||Rho GDP-dissociation inhibitor 2, Rho GDI 2, Ly-GDI, Rho-GDI beta, ARHGDIB, GDIA2, GDID4, RAP1GN1|
|Reconstitution & Storage||Store at 2°C to 8°C degrees. Do not freeze.|
|Precautions||ARHGDIB / D4 GDI Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||GDIA2, GDID4, RAP1GN1|
|Function||Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them (PubMed:8356058, PubMed:7512369). Regulates reorganization of the actin cytoskeleton mediated by Rho family members (PubMed:8262133).|
|Cellular Location||Cytoplasm, cytosol|
|Tissue Location||Detected in bone marrow, thymus and spleen.|
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Provided below are standard protocols that you may find useful for product applications.
Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them.
Scherle P.,et al.Proc. Natl. Acad. Sci. U.S.A. 90:7568-7572(1993).
Leffers H.,et al.Exp. Cell Res. 209:165-174(1993).
Lelias J.M.,et al.Proc. Natl. Acad. Sci. U.S.A. 90:1479-1483(1993).
Puhl H.L. III,et al.Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases.
Goshima N.,et al.Nat. Methods 5:1011-1017(2008).
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