|Application ||IHC-P, E|
|Reactivity||Human, Mouse, Rat, Rabbit, Hamster, Monkey, Pig, Horse, Bovine, Dog|
|Dilution||ELISA (1:1000), IHC-P (5 µg/ml),|
|Other Names||Brain-specific angiogenesis inhibitor 2, BAI2|
|Target/Specificity||KLH conjugated synthetic peptide comprising amino acids 1558 - 1572 [WEPTEPPDGDFQTEV] of the human brain-specific angiogenesis inhibitor 2 (BAI2) protein.|
|Reconstitution & Storage||Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.|
|Precautions||ADGRB2 / BAI2 Antibody (aa1558-1572) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Orphan G-protein coupled receptor involved in cell adhesion and probably in cell-cell interactions. Activates NFAT- signaling pathway, a transcription factor, via the G-protein GNAZ (PubMed:20367554, PubMed:28891236). Involved in angiogenesis inhibition (By similarity).|
|Cellular Location||Cell membrane; Multi-pass membrane protein|
|Tissue Location||Strongly expressed in brain. Also detected in heart, thymus, skeletal muscle, and different cell lines|
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Provided below are standard protocols that you may find useful for product applications.
Might be involved in angiogenesis inhibition.
Shiratsuchi T.,et al.Cytogenet. Cell Genet. 79:103-108(1997).
Suwa M.,et al.Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases.
Gregory S.G.,et al.Nature 441:315-321(2006).
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