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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   ICAM-1 / CD54 Antibody (clone 15.2)   

ICAM-1 / CD54 Antibody (clone 15.2)

Mouse Monoclonal Antibody

     
  • IHC - ICAM-1 / CD54 Antibody (clone 15.2) ALS12821
    Anti-ICAM-1 antibody IHC of human lung.
  • IHC - ICAM-1 / CD54 Antibody (clone 15.2) ALS12821
    Anti-ICAM-1 antibody IHC of human spleen.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, IP, IHC-Fr, Flo
Primary Accession P05362
Reactivity Human, Pig
Host Mouse
Clonality Monoclonal
Clone Names 15.2
Calculated MW 58kDa
Dilution Flo (1:50-1:100), IHC-P (10 µg/ml),
Additional Information
Gene ID 3383
Other Names Intercellular adhesion molecule 1, ICAM-1, Major group rhinovirus receptor, CD54, ICAM1
Target/Specificity Recognizes the human CD54 cell surface antigen, a 90kD glycoprotein also known as ICAM-1. CD54 is expressed by many cells following activation by inflammatory mediators. Clone 15.2 is reported to block CD54 function.
Reconstitution & Storage +4°C or -20°C, Avoid repeated freezing and thawing.
PrecautionsICAM-1 / CD54 Antibody (clone 15.2) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ICAM1
Function ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans- endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation.
Cellular Location Membrane; Single-pass type I membrane protein
Research Areas
Citations (0)

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Background

ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans- endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.

References

Simmons D.,et al.Nature 331:624-627(1988).
Staunton D.E.,et al.Cell 52:925-933(1988).
Tomassini J.E.,et al.Proc. Natl. Acad. Sci. U.S.A. 86:4907-4911(1989).
Voraberger G.F.,et al.J. Immunol. 147:2777-2786(1991).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.

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$ 395.00
Cat# ALS12821
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