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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   LIM Protein / LPP Antibody   

LIM Protein / LPP Antibody

Mouse Monoclonal Antibody

     
  • WB - LIM Protein / LPP Antibody ALS12838
    Western blot using LPP mouse monoclonal antibody against HeLa (1), NIH/3T3 (2), COS (3), Caki...
  • IF - LIM Protein / LPP Antibody ALS12838
    Confocal immunofluorescence of COS cells using LPP mouse monoclonal antibody (green).
  • IF - LIM Protein / LPP Antibody ALS12838
    Confocal immunofluorescence of HeLa cells using LPP mouse monoclonal antibody (green).
  • IHC - LIM Protein / LPP Antibody ALS12838
    Anti-LPP antibody IHC of human vessels.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, E
Primary Accession Q93052
Reactivity Human
Host Mouse
Clonality Monoclonal
Calculated MW 66kDa
Dilution ELISA (1:10000), IF (1:200-1:1000), IHC-P (1:200), WB (1:500-1:2000) ,
Additional Information
Gene ID 4026
Other Names Lipoma-preferred partner, LIM domain-containing preferred translocation partner in lipoma, LPP
Target/Specificity Purified truncated recombinant LPP-His is expressed in E. coli strain BL21 (DE3).
PrecautionsLIM Protein / LPP Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name LPP
Function May play a structural role at sites of cell adhesion in maintaining cell shape and motility. In addition to these structural functions, it may also be implicated in signaling events and activation of gene transcription. May be involved in signal transduction from cell adhesion sites to the nucleus allowing successful integration of signals arising from soluble factors and cell-cell adhesion sites. Also suggested to serve as a scaffold protein upon which distinct protein complexes are assembled in the cytoplasm and in the nucleus.
Cellular Location Nucleus. Cytoplasm. Cell junction. Cell membrane. Note=Found in the nucleus, in the cytoplasm and at cell adhesion sites. Shuttles between the cytoplasm and the nucleus. It has been found in sites of cell adhesion such as cell-to-cell contact and focal adhesion which are membrane attachment sites of cells to the extracellular matrix. Mainly nuclear when fused with HMGA2/HMGIC and KMT2A/MLL1
Tissue Location Expressed in a wide variety of tissues but no or very low expression in brain and peripheral leukocytes
Volume 50 µl
Research Areas
Citations (0)

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Background

May play a structural role at sites of cell adhesion in maintaining cell shape and motility. In addition to these structural functions, it may also be implicated in signaling events and activation of gene transcription. May be involved in signal transduction from cell adhesion sites to the nucleus allowing successful integration of signals arising from soluble factors and cell-cell adhesion sites. Also suggested to serve as a scaffold protein upon which distinct protein complexes are assembled in the cytoplasm and in the nucleus.

References

Petit M.M.R.,et al.Genomics 36:118-129(1996).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Lemke I.,et al.Cytogenet. Cell Genet. 95:153-156(2001).
Petit M.M.,et al.Cancer Genet. Cytogenet. 106:18-23(1998).

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$ 395.00
Cat# ALS12838
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