Foundational characteristics of cancer include proliferation, angiogenesis, migration, evasion of apoptosis, and cellular immortality. Find key markers for these cellular processes and antibodies to detect them.
The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.
The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.
FEZ1 Antibody (Internal)
Goat Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | Q99689 |
| Reactivity | Human, Rat, Rabbit, Hamster, Monkey, Horse, Bovine, Dog |
| Host | Goat |
| Clonality | Polyclonal |
| Calculated MW | 45kDa |
| Dilution | ELISA (1:128000), IHC-P (5 µg/ml), WB (1:128000) |
| Gene ID | 9638 |
|---|---|
| Other Names | Fasciculation and elongation protein zeta-1, Zygin I, Zygin-1, FEZ1 |
| Target/Specificity | Human FEZ1. This antibody is expected to recognize isoform 1 (NP_005094.1) only. |
| Reconstitution & Storage | Store at -20°C. Minimize freezing and thawing. |
| Precautions | FEZ1 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | FEZ1 |
|---|---|
| Function | May be involved in axonal outgrowth as component of the network of molecules that regulate cellular morphology and axon guidance machinery. Able to restore partial locomotion and axonal fasciculation to C.elegans unc-76 mutants in germline transformation experiments. May participate in the transport of mitochondria and other cargos along microtubules. |
| Cellular Location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cell membrane. Note=Colocalizes with both, alpha- and gamma-tubulin Translocated from the plasma membrane to the cytoplasm by activation of the PKC zeta (By similarity). |
| Tissue Location | Mainly expressed in brain. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
May be involved in axonal outgrowth as component of the network of molecules that regulate cellular morphology and axon guidance machinery. Able to restore partial locomotion and axonal fasciculation to C.elegans unc-76 mutants in germline transformation experiments. May participate in the transport of mitochondria and other cargos along microtubules.
References
Bloom L.,et al.Proc. Natl. Acad. Sci. U.S.A. 94:3414-3419(1997).
Sugita S.,et al.Submitted (AUG-1996) to the EMBL/GenBank/DDBJ databases.
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Halleck A.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Okumura F.,et al.J. Biol. Chem. 279:53533-53543(2004).
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.
Ordering Information
Other Products
Shipping Information
