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FEZ1 Antibody (Internal)

Goat Polyclonal Antibody

     
  • IHC - FEZ1 Antibody (Internal) ALS12861
    Anti-FEZ1 antibody IHC of human brain, cortex.
  • IHC - FEZ1 Antibody (Internal) ALS12861
    Anti-FEZ1 antibody IHC of human colon, submucosal plexus.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q99689
Reactivity Human, Rat, Rabbit, Hamster, Monkey, Horse, Bovine, Dog
Host Goat
Clonality Polyclonal
Calculated MW 45kDa
Dilution ELISA (1:128000), IHC-P (5 µg/ml), WB (1:128000)
Additional Information
Gene ID 9638
Other Names Fasciculation and elongation protein zeta-1, Zygin I, Zygin-1, FEZ1
Target/Specificity Human FEZ1. This antibody is expected to recognize isoform 1 (NP_005094.1) only.
Reconstitution & Storage Store at -20°C. Minimize freezing and thawing.
PrecautionsFEZ1 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FEZ1
Function May be involved in axonal outgrowth as component of the network of molecules that regulate cellular morphology and axon guidance machinery. Able to restore partial locomotion and axonal fasciculation to C.elegans unc-76 mutants in germline transformation experiments. May participate in the transport of mitochondria and other cargos along microtubules.
Cellular Location Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cell membrane. Note=Colocalizes with both, alpha- and gamma-tubulin. Translocated from the plasma membrane to the cytoplasm by activation of the PKC zeta (By similarity)
Tissue Location Mainly expressed in brain.
Research Areas
Citations (0)

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Background

May be involved in axonal outgrowth as component of the network of molecules that regulate cellular morphology and axon guidance machinery. Able to restore partial locomotion and axonal fasciculation to C.elegans unc-76 mutants in germline transformation experiments. May participate in the transport of mitochondria and other cargos along microtubules.

References

Bloom L.,et al.Proc. Natl. Acad. Sci. U.S.A. 94:3414-3419(1997).
Sugita S.,et al.Submitted (AUG-1996) to the EMBL/GenBank/DDBJ databases.
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Halleck A.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Okumura F.,et al.J. Biol. Chem. 279:53533-53543(2004).

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$ 395.00
Cat# ALS12861
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